BDBM38034 3-(3-(naphthalen-1-yloxy)propyl)-6-phenylbenzo[b]thiophene-2-carboxylic acid::US10093640, Example 13::US10844032, Example 13
SMILES OC(=O)c1sc2cc(ccc2c1CCCOc1cccc2ccccc12)-c1ccccc1
InChI Key InChIKey=JKKFKPJIXZFSSB-CBZIJGRNSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 38034
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [172-327](Homo sapiens (Human))
Vanderbilt University
US Patent
Vanderbilt University
US Patent
Affinity DataKi: 5.50E+3nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair